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DSS-induced colitis in mice elicited pronounced symptoms, including reduced locomotor activity, decreased consumption of food and water, dull and lifeless fur, signs of depression-like behavior, huddling behavior, perianal swelling and congestion, diarrhea, bloody stools, and substantial weight loss

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Last year, the agency partnered with Genomics England to use the UK Biobank to delve deeper into the risk of pancreatitis among GLP-1 users, to see if there is a genetic factor that elevates the risk